NMR Characterization and QC Testing

Eurofins Spinnovation Analytical provides NMR characterization and QC-testing solutions for raw materials, drug substances and drug products.

Eurofins European Centre of Excellence for NMR

We deliver you Solution- and Solid-State NMR (ssNMR) contract research and method development services. We support projects and testing related to ingredients, polymers, pharmaceutical drug substances and pharmaceutical drug products. Our state-of-the-art equipment allows high capacity, optimum sensitivity and fast turn-around, supporting development and product release. Our broad scope of NMR capabilities and knowledge are centralized in the European Centre of Excellence for NMR in Oss, The Netherlands.


  • 400MHz WB Avance Bruker fitted with a dedicated 19F-NMR set up allowing 1H-19F CPMAS experiment, 10 positions sample changer , Probes: 4mm MAS (1H, 19F, X), 7mm MAS (1H, X)
  • 2 x 500MHz NMR Bruker Avance III, BBFO probe and TCI cryorpobe, SampleJet
  • 400MHz NMR Bruker Avance III, BBFO probe (1H, 13C, 31P, 19F), SampleJet
  • LC-SPE/NMR capability

Solutions and Applications

  • Solid-state characterization: crystal polymorphism, solid-state process development, impurity ID, limit test, etc.
  • Identification of unknown (impurity identification, metabolite identification)
  • qNMR to qualify reference compounds
  • High throughput QC of compound library
  • Compound library chemical shift encoding and protein ligand NMR binding assays
  • 3D-NMR structure characterization


GMP NMR testing

We deliver you simple and easy access to GMP NMR QC-testing services for your raw materials and pharmaceutical products. We perform Pharmacopoeia NMR test methods or can develop and validate NMR based methods when required.


  • 500MHz NMR Bruker Avance III
  • BBFO and TCI cryorpobe
  • SampleJet
  • GMP certified, FDA inspected

Pharmacopoeia methods (Ph. Eur. / USP)

  • Heparin (sodium/calcium/LMWH)
  • Poloxamer
  • Enoxaparin
  • Polyoxyl
  • Hydroxypropyl
  • Chitosan
  • Oxytocin
  • Goserelin
  • Medronic acid
  • Buserelin
  • Animal oil
  • Lauromacrogol
  • Pemetrexed disodium hydrate
  • Cleint internal methods

Contact our team of specialists for questions and requests about NMR characterization
and testing services:  Contact us here.

Questions? Call us now

+31 (0)24 240 3400