NMR Characterization and QC Testing
Eurofins Spinnovation Analytical provides NMR characterization and QC-testing solutions for raw materials, drug substances and drug products.
Eurofins European Centre of Excellence for NMR
We deliver you Solution- and Solid-State NMR (ssNMR) contract research and method development services. We support projects and testing related to ingredients, polymers, pharmaceutical drug substances and pharmaceutical drug products. Our state-of-the-art equipment allows high capacity, optimum sensitivity and fast turn-around, supporting development and product release. Our broad scope of NMR capabilities and knowledge are centralized in the European Centre of Excellence for NMR in Oss, The Netherlands.
- 400MHz WB Avance Bruker fitted with a dedicated 19F-NMR set up allowing 1H-19F CPMAS experiment, 10 positions sample changer , Probes: 4mm MAS (1H, 19F, X), 7mm MAS (1H, X)
- 2 x 500MHz NMR Bruker Avance III, BBFO probe and TCI cryorpobe, SampleJet
- 400MHz NMR Bruker Avance III, BBFO probe (1H, 13C, 31P, 19F), SampleJet
- LC-SPE/NMR capability
Solutions and Applications
- Solid-state characterization: crystal polymorphism, solid-state process development, impurity ID, limit test, etc.
- Identification of unknown (impurity identification, metabolite identification)
- qNMR to qualify reference compounds
- High throughput QC of compound library
- Compound library chemical shift encoding and protein ligand NMR binding assays
- 3D-NMR structure characterization
GMP NMR testing
We deliver you simple and easy access to GMP NMR QC-testing services for your raw materials and pharmaceutical products. We perform Pharmacopoeia NMR test methods or can develop and validate NMR based methods when required.
- 500MHz NMR Bruker Avance III
- BBFO and TCI cryorpobe
- GMP certified, FDA inspected
Pharmacopoeia methods (Ph. Eur. / USP)
- Heparin (sodium/calcium/LMWH)
- Medronic acid
- Animal oil
- Pemetrexed disodium hydrate
- Cleint internal methods
Contact our team of specialists for questions and requests about NMR characterization
and testing services: Contact us here.